High sister chromatid exchange among a sample of traffic policemen in Bangkok, Thailand.

Monitoring of human populations at risk by different cytogenetic end points.

Humans are exposed to a large number of environmental genotoxic agents. These can increase the probability that somatic mutation will occur. The use of genotoxicity testing is essential for assessment of potential human toxicity so that hazards can be prevented. Cytogenetic monitoring of human populations exposed to chemicals has proved to be a useful tool for detecting the chemical mutagenic e...

Sister chromatid exchange analysis in some Holstein bulls

Chromosomal appearance of 12 Holstein bulls selected for artificial inseminations were examined bysister chromatid exchanges (SCEs). For differential staining of sister chromatids bromodeoxyuridine (BrdU)was inoculated in lymphocyte cultures. The mean, maximum and minimum number of SCE per cell weredetermined 6.8 ± 1.14, 8.3 ± 1.1 and 5.7 ± 1.5, respectively. SCE frequencies of all animals were...

Study of the Effect of MMC on the Sister Chromatid Exchange in the Human Lymphocytes

Some environmental mutagenic agents cause genomic instability and increase susceptibility of DNA damage. One of them is mitomycin C which is connected to DNA as an alkylating factor and affects susceptible cells to reduction reactions. This drug is used in chemotherapy and treatment of tumors. Study of genomic instability in the presence of different concentrations of MMC can show susceptibilit...

Rabies Vaccination Among Foreigners in Thailand: A Summary From a Medical Center

Blood Toluene and Genotoxicity in Gasoline Station Workers in Bangkok: a Preliminary Study

Toluene is widely used as an industrial solvent and is usually produced in the processes of making gasoline. Inhaled toluene may cause genotoxicity and other adverse health effects. This study aimed to ascertain the relation between blood toluene exposure and genotoxicity, as measured by sister chromatid exchange (SCE), by comparing gasoline station workers to controls. Mean blood toluene and S...